Preholo-Proteasome from Beta 3 D205 deletion
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8u6y
Q-score: 0.513
Velez B, Walsh Jr RM, Rawson S, Razi A, Adams L, Perez EF, Jiao F, Blickling M, Rajakumar T, Fung D, Huang L, Hanna J
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01262-1 Pubmed: 38600323 ]
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome chaperone 1 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-3 (27 kDa, Protein from Saccharomyces cerevisiae S288C)
- Preholo-proteasome from beta 3 d205 deletion mutant (750 kDa, Complex from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-1 (23 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-6 (26 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome assembly chaperone 2 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-7 (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome maturation factor ump1 (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-5 (31 kDa, Protein from Saccharomyces cerevisiae S288C)
Proteasome 20S Core Particle from Beta 3 D205 deletion
Resolution: 2.16 Å
EM Method: Single-particle
Fitted PDBs: 8u7u
Q-score: 0.688
Velez B, Walsh Jr RM, Rawson S, Razi A, Adams L, Perez EF, Jiao F, Blickling M, Rajakumar T, Fung D, Huang L, Hanna J
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01262-1 Pubmed: 38600323 ]
- Proteasome subunit alpha type-5 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-3 (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-7 (31 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome 20s core particle from beta 3 d205 deletion mutant (700 kDa, Complex from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-1 (23 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-1 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-6 (26 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-4 (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-7 (29 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-2 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-6 (25 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-2 (27 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit beta type-5 (31 kDa, Protein from Saccharomyces cerevisiae S288C)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Saccharomyces cerevisiae S288C)
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8oix
Q-score: 0.581
Silhan J, Fajtova P, O'Donoghue A, Boura E
To Be Published
- Proteasome subunit alpha type (27 kDa, Protein from Trichomonas vaginalis G3)
- Family t1, proteasome beta subunit, threonine peptidase (26 kDa, Protein from Trichomonas vaginalis G3)
- Family t1, proteasome alpha subunit, threonine peptidase (25 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome endopeptidase complex (26 kDa, Protein from Trichomonas vaginalis G3)
- Ternary complex of 20s proteasome from trichomonas vaginalis (704 kDa, Complex from Trichomonas vaginalis G3)
- Family t1, proteasome alpha subunit, threonine peptidase (25 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome subunit beta (22 kDa, Protein from Trichomonas vaginalis G3)
- (3ar,6r,6as)-6-((s)-((s)-cyclohex-2-enyl)(hydroxy)methyl)-6a-methyl-4-oxo-hexahydro-2h-furo[3,2-c]pyrrole-6-carbaldehyde (279 Da, Ligand)
- Proteasome subunit beta (21 kDa, Protein from Trichomonas vaginalis G3)
- Family t1, proteasome alpha subunit, threonine peptidase (26 kDa, Protein from Trichomonas vaginalis G3)
- Family t1, proteasome alpha subunit, threonine peptidase (27 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome subunit alpha type (27 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome subunit beta (21 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome subunit alpha type (26 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome subunit beta (25 kDa, Protein from Trichomonas vaginalis G3)
- Proteasome subunit beta (23 kDa, Protein from Trichomonas vaginalis G3)
CryoEM structure of human DDB1-DCAF12 in complex with MAGEA3
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8t9a
Q-score: 0.386
Duda D, Righetto G, Li Y, Loppnau P, Seitova A, Santhakumar V, Halabelian L, Yin Y
To Be Published
- Ternary complex of dcaf12-ddb1-magea3 (Complex from Homo sapiens)
- Dna damage-binding protein 1 (127 kDa, Protein from Homo sapiens)
- Ddb1- and cul4-associated factor 12 (52 kDa, Protein from Homo sapiens)
- Melanoma-associated antigen 3 (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 8wqa
Q-score: 0.362
To Be Published
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of ccdc89 (conformation 1) (Complex from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Coiled-coil domain-containing protein 89 (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wqb
Q-score: 0.39
To Be Published
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of ccdc89 (conformation 2) (Complex from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Coiled-coil domain-containing protein 89 (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8wqc
Q-score: 0.352
To Be Published
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with the c-degron of cdk5r1 (Complex from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Nedd8 (8 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
Local refinement of FEM1B bound with the C-degron of CCC89
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8wqd
Q-score: 0.5
To Be Published
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8wqe
Q-score: 0.372
To Be Published
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of cux1 (conformation 1) (Complex from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Protein casp (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2)
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 8wqf
Q-score: 0.439
To Be Published
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of cux1 (conformation 2) (Complex from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Protein casp (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)